The interaction between cancer cells and immune cells is important for the cancer development. However, much attention has been given to T cells and macrophages. Being the most abundant leukocytes in the blood, the functions of neutrophils in cancer have been underdetermined. They have long been considered an “audience” in the development of cancer. However, emerging evidence indicate that
Neutrophils can also aid tumor cell killing. CCL2 produced by the primary tumor can activate neutrophils in the premetastatic niche to produce hydrogen peroxide, providing an efficient tumor cell killing mechanism. IFN-β has also been shown to increase neutrophil antitumor potential by increasing NET capacity and cytotoxicity toward tumor cells.
The neutropenic diet does allow fresh fruits and vegetables, thoroughly cooked and commercially packaged meats, fish, poultry, and most breads and grains. Neutropenia also requires modifications to one’s lifestyle with precautions and steps to take to prevent further complications and recurring infections.
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how to increase neutrophils naturally